Early Warning and Event Forecasting

At certain times of year, naturally occurring marine algae can proliferate and pose a threat to human health from the production of potent bio-toxins. These “Harmful Algal Blooms” (HABs) are particularly damaging when algal bio-toxins become concentrated in the bodies of filter feeding bi-valve shellfish, posing a risk to human health when consumed.

The current, statutory method for the monitoring of HABs involves the delivery of water samples to a centralised lab and analysis for certain algal species by microscopy. Despite being expensive, this incurs a severe time delay between the detection of a HAB event and the enation of the necessary intervention such as a delay or acceleration in shellfish harvest. 

Main Aims of Cytometer

Cytometer Deployment
Cytometer Deployment

The aim of this technology is to improve early warning and event forecasting of harmful algal blooms within and around shellfisheries by developing existing, state of the art, lab-on-chip technology into a new, portable tool that will enable end-users (i.e., shellfish producers, and statutory monitoring authorities) to undertake HAB surveillance in the field. This technology takes the form of a micro-cytometer, a device that measures the properties of cells as they pass through a narrow channel. While conventional cytometers only measure the optical properties of cells, our system (CYTOCHIP) measures multiple optical and electrical properties simultaneously, providing excellent discrimination of cell types and differentiation of toxin-producing and non-toxic species. These capabilities are being exploited to help shellfish producers and authorities to protect consumers and public health, and reduce the costs associated with the existing, delayed analysis methods.

More Information

Simultaneous high speed optical and impedance analysis of single particles with a microfluidic cytometer

Authors

Barat, David; Spencer, Daniel; Benazzi, Giuseppe; Mowlem, Matthew Charles; Morgan, Hywel. 2012 Simultaneous high speed optical and impedance analysis of single particles with a microfluidic cytometer. Lab on a Chip, 12 (1). 118-126. 10.1039/c1lc20785g

Publication year

2012

Publication type

Article

Discrimination of microplastics and phytoplankton using impedance cytometry

Authors

Butement, Jonathan T.; Wang, Xiang; Siracusa, Fabrizio; Miller, Emily; Pabortsava, Katsiaryna ORCID: https://orcid.org/0000-0002-9808-012X; Mowlem, Matthew; Spencer, Daniel; Morgan, Hywel. 2024 Discrimination of microplastics and phytoplankton using impedance cytometry. ACS Sensors. 10.1021/acssensors.4c01353

Publication year

2024

Publication type

Article